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2019()--

There is a high demand for advanced, image‐based, automated high‐content screening (HCS) approaches to facilitate phenotypic screening in 3D cell culture models. A major challenge lies in retaining the resolution of fine cellular detail but at the same time imaging multicellular structures at

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Inflammation associated with noise-induced hearing loss

Nov 27, 2019 · Many other DAMPs can be common cell constituents. However, we employed the same expression database as above to assess their presence in HCs. Most of the DAMPs listed in Table I were expressed by HCs, although as expected the genes for cathelicidin, eosinophil-derived neurotoxin and antibodies were absent. Particularly high levels of

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csair

2018heatconhcs9200b ★ 1 hcs-dcas () hcs2036-01-022. 90

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Intravitreal Avastin

DOI 10.1016/j.ophtha.2012.01.022. 7. The CATT Research Group. Ranibizumab and Bevacizumab for neovascular age-related macular degeneration. New England Journal of Medicine 2011;364(20)1897-908. DOI 10.1056/NEJMoa1102673. Appendix 1 Covered Diagnosis Codes ICD-10 ICD-10 Description

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Frontiers The Regulatory Role of Long Noncoding RNAs in

Mar 22, 2019 · Stroke results in high morbidity and high mortality worldwide, with ischemic stroke accounting for 80% to 85%. As effective treatments for ischemic stroke remain limited because of the narrow therapeutic time window, a better understanding of the pathologic mechanism and new therapeutic intervention targets are needed. Due to the development of next-generation sequencing

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Intrinsic functional connectivity variance and state

Xu Han, Xiaowei Wu, Yao Wang, Yawen Sun, Weina Ding, Mengqiu Cao, Yasong Du, Fuchun Lin, Yan Zhou, Alterations of Resting-State Static and Dynamic Functional Connectivity of the Dorsolateral Prefrontal Cortex in Subjects with Internet Gaming Disorder, Frontiers in Human Neuroscience, 10.3389/fnhum.2018.00041, 12, (2018).

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environmental impact on cement industry

13.09.2018· The Crushing Environmental Impact of China's Cement Industry September 13, 2018 By Kimberly Yang China—the world's fastest-growing economy with the largest population—leads the world in cement production, the critical ingredient that has built China's mammoth cities, sprawling roads, and other infrastructure.

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Directives Directive Number Occupational Safety and

Directives Directive Number. OSHA Directives are written statements of policy and procedure on a single subject, which generally include implementation guidelines and

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Kinetic Study of Carbon Monoxide and Propylene Oxidation

This article is cited by 386 publications. Andreas M. Gänzler, Maria Casapu, Dmitry E. Doronkin, Florian Maurer, Patrick Lott, Pieter Glatzel, Martin Votsmeier, Olaf Deutschmann, Jan-Dierk Grunwaldt. Unravelling the Different Reaction Pathways for Low Temperature CO Oxidation on Pt/CeO2 and Pt/Al2O3 by Spatially Resolved StructureActivity Correlations.

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Implementation of massive sequencing in the genetic

Approximately 5 to 10% of all cancers are caused by inherited germline mutations, many of which are associated with different Hereditary Cancer Syndromes (HCS). In the context of the Program of Hereditary Cancer of the Valencia Community, individuals belonging to specific HCS and their families receive genetic counselling and genetic testing according to internationally established guidelines.

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OPTN recruitment to a Golgi-proximal compartment regulates

Jun 15, 2020 · Optineurin (OPTN) is a multifunctional protein involved in autophagy and secretion, as well as nuclear factor κB (NF-κB) and IRF3 signalling, and OPTN mutations are associated with several human diseases. Here, we show that, in response to viral RNA, OPTN translocates to foci in the perinuclear region, where it negatively regulates NF-κB and IRF3 signalling pathways and downstream pro

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Frontiers A Voxel-Wise Meta-Analysis of Gray Matter

Jun 26, 2018 · Objective To identify the consistent gray matter (GM) volume changes from the whole brain voxel-based morphometry (VBM) studies on essential tremor (ET).Methods The whole brain VBM studies comparing ET patients and healthy controls (HCs) were systematically searched in the PubMed, Embase and Web of Science from January 2000 to December 2017.

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Apoptosis-derived membrane vesicles drive the cGASSTING

Objective Despite the importance of type I interferon (IFN-I) in systemic lupus erythematosus (SLE) pathogenesis, the mechanisms of IFN-I production have not been fully elucidated. Recognition of nucleic acids by DNA sensors induces IFN-I and interferon-stimulated genes (ISGs), but the involvement of cyclic guanosine monophosphate (GMP)AMP synthase (cGAS) and stimulator of interferon genes

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2020 University College London

2020. Lu, X., Bertei, A., Finegan, D.P., Tan, C., Daemi, S.R., Weaving, J.S., Kendrick, E. (2020). 3D microstructure design of lithium-ion battery electrodes

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Orbitofrontal dysfunction during the reward process in

May 01, 2019 · The IGT was conducted on a PC via a customized program written using E-PRIME 1.1 software (Psychology Software Tools, Pittsburgh, PA, USA). In the present study, we modified the monetary unit to New Taiwan Dollars by multiplying amounts by 30 from the original version of the IGT (Bechara et al., 1994).Participants were initially given an NTD 60,000 monetary value and were

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Background journals.plos

* E-mail [email protected] 21 2 2018 2018 13 2 e0192306 4 7 2017 22 1 2018 2018 Sustersic et al This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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